[1]田纯纯,申黎艳,徐苏苏,等.联合营养门诊饮食指导对2型糖尿病病人治疗效果[J].青岛大学医学院学报,2017,53(03):324-327.[doi:10.13361/j.qdyxy.201703020]
 TIAN Chunchun,SHEN Liyan,XU Susu,et al.THERAPEUTIC EFFECT OF ENDOCRINE THERAPY COMBINED WITH DIETARY GUIDANCE IN NUTRITION CLINIC IN PATIENTS WITH TYPE 2 DIABETES[J].Acta Aacademiae Medicinae Qingdao,2017,53(03):324-327.[doi:10.13361/j.qdyxy.201703020]
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联合营养门诊饮食指导对2型糖尿病病人治疗效果()
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《青岛大学医学院学报》[ISSN:1672-4488/CN:37-1356/R]

卷:
第53卷
期数:
2017年03期
页码:
324-327
栏目:
出版日期:
2017-08-07

文章信息/Info

Title:
THERAPEUTIC EFFECT OF ENDOCRINE THERAPY COMBINED WITH DIETARY GUIDANCE IN NUTRITION CLINIC IN PATIENTS WITH TYPE 2 DIABETES
文章编号:
1672-4488(2017)03-0324-04
作者:
田纯纯申黎艳徐苏苏朱海冬孟冬梅
青岛大学附属医院内分泌与代谢性疾病科,山东 青岛 266003
Author(s):
TIAN Chunchun SHEN Liyan XU Susu ZHU Haidong MENG Dongmei
Department of Endocrinology and Metabolism, The Affiliated Hospital of Qingdao University, Qingdao 266003, China
关键词:
糖尿病2型营养疗法门诊医疗饮食习惯
Keywords:
diabetes mellitustype 2 nutrition therapy ambulatory care food habits
分类号:
R587.1
DOI:
10.13361/j.qdyxy.201703020
文献标志码:
A
摘要:
目的 探讨内分泌门诊联合营养门诊饮食指导对血糖控制不达标的2型糖尿病病人的治疗效果及临床意义。
方法 将125例血糖控制不达标的2型糖尿病病人随机分为对照组(n=65)与观察组(n=60)。对照组给予常规内分泌门诊治疗,观察组在内分泌门诊治疗基础上同时给予营养科饮食指导,观察期为3个月。比较两组治疗前后血糖、糖化血红蛋白(HbA1c)、血脂、体质量及腰围变化。
结果 观察组治疗后体质量、腰围、胆固醇(TC)、低密度脂蛋白(LDL)、游离脂肪酸(FFA)、HbA1c、空腹血糖(FBG)、餐后2 h血糖(2hPBG)水平均较治疗前显著降低(t=3.464~7.492,P<0.05),高密度脂蛋白(HDL)水平则较治疗前显著上升(t=-3.510,P<0.05),三酰甘油(TG)水平与治疗前比较差异无显著性(P>0.05)。对照组治疗后体质量、腰围、TG水平与治疗前比较差异无显著性(P>0.05),TC、LDL、FFA、HbA1c、FBG、2hPBG水平均较治疗前显著降低(t=2.751~6.791,P<0.05),HDL水平则较治疗前显著上升(t=-3.322,P<0.05)。观察组治疗前后体质量、腰围、TC、LDL下降幅度均大于对照组,差异有统计学意义(t=2.697~3.284,P<0.05)。两组治疗前后TG、HDL、FFA、HbA1c、FBG、2hPBG差值比较差异无统计学意义(P>0.05)。以HbA1c<6.5%、FBG<7 mmol/L为血糖控制达标,两组达标率比较差异有显著性(χ2=5.928、4.147,P<0.05)。以2hPBG<10 mmol/L为血糖控制达标,两组达标率比较差异无统计学意义(P>0.05)。
结论 联合营养科门诊饮食指导可使血糖控制不达标的2型糖尿病病人血糖、血脂、体质量及腰围得到控制,改善腹型肥胖,提高HbA1c达标率。
Abstract:
Objective  To investigate the therapeutic effect and clinical significance of endocrine therapy combined with dietary guidance in type 2 diabetic patients with poor blood glucose control.
Methods  A total of 125 type 2 diabetic patients with poor blood glucose control were randomly divided into control group with 65 patients and observation group with 60 patients. The patients in the control group were given conventional endocrine therapy, and those in the observation group were given dietary guidance in addition to the endocrine therapy. The observation period was 3 months. The two groups were compared in terms of the changes in blood glucose, glycosylated hemoglobin (HbA1c), blood lipids, body weight, and waist circumference after treatment.
Results  The observation group had significant reductions in body weight, waist circumference, total cholesterol (TC), low-density lipoprotein (LDL), free fatty acid (FFA), HbA1c, fasting blood glucose (FBG), and 2 h postprandial blood glucose (2hPBG) (t=3.464-7.492,P<0.05) and a significant increase in high-density lipoprotein (HDL) after treatment (t=-3.510,P<0.05). The control group had no significant changes in body weight, waist circumference, and TG after treatment and had significant reductions in TC, LDL, FFA, HbA1c, FBG, and 2hPBG (t=2.751-6.791,P<0.05), as well as a significant increase in HDL (t=-3.322,P<0.05). Compared with the control group, the observation group had significantly greater reductions in body weight, waist circumference, TC, and LDL after treatment (t=2.697-3.284,P<0.05). There were no significant differences in TG, HDL, FFA, HbA1c, FBG, and 2hPBG before and after treatment between the two groups (P>0.05). With HbA1c<6.5% and FBG<7 mmol/L as the standard, there was a significant difference in control rate between the two groups (χ2=5.928 and 4.147,P<0.05). With 2hPBG<10 mmol/L as the standard, there was no significant difference in control rate between the two groups (P>0.05).
Conclusion  In type 2 diabetic patients with poor blood glucose control, endocrine therapy combined with dietary guidance can help to control blood glucose, blood lipids, body weight, and waist circumference, improve abdominal obesity, and increase the control rate of HbA1c.
更新日期/Last Update: 2017-08-13