[1]迟媛媛,钟洪啸,王芸,等.新生儿非ABO溶血病的血清抗体分析[J].青岛大学医学院学报,2017,53(03):330-332.[doi:10.13361/j.qdyxy.201703022]
 CHI Yuanyuan,ZHONG Hongxiao,WANG Yun,et al.SERUM ANTIBODIES IN NEONATES WITH NON-ABO HEMOLYTIC DISEASE[J].Acta Aacademiae Medicinae Qingdao,2017,53(03):330-332.[doi:10.13361/j.qdyxy.201703022]
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新生儿非ABO溶血病的血清抗体分析()
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《青岛大学医学院学报》[ISSN:1672-4488/CN:37-1356/R]

卷:
第53卷
期数:
2017年03期
页码:
330-332
栏目:
出版日期:
2017-08-07

文章信息/Info

Title:
SERUM ANTIBODIES IN NEONATES WITH NON-ABO HEMOLYTIC DISEASE
文章编号:
1672-4488(2017)03-0330-03
作者:
迟媛媛钟洪啸王芸倪照兰张迪周雨笋
青岛市妇女儿童医院输血科,山东 青岛 266034
Author(s):
CHI Yuanyuan ZHONG Hongxiao WANG Yun NI Zhaolan ZHANG Di ZHOU Yusun
Department of Blood Transfusion, Qingdao Women and Children Hospital, Qingdao 266034, China
关键词:
幼红细胞增多症胎儿血型抗原抗体
Keywords:
polycythemia fetal blood group antigens antibodies
分类号:
R722.18
DOI:
10.13361/j.qdyxy.201703022
文献标志码:
A
摘要:
目的 探讨新生儿非ABO溶血病的血清抗体情况,为其治疗和预防提供参考依据。
方法 对30例非ABO溶血病新生儿血清抗体进行检测,25例病儿母亲有生产史,22例有流产史,2例为第一胎。
结果 抗-D者16例,抗-D联合抗-E者1例,共17例,占56.7%;抗-E者5例,抗-E联合抗-c者5例,抗-E联合抗-Jkb者1例,共11例,占36.7%;抗-C者1例,MNS血型系统抗-M抗体1例,各占3.3%。
结论 临床应重视对孕妇进行产前不规则抗体的筛查,尤其是有生产史或流产史的孕妇,应加强对E抗原的检测。
Abstract:
Objective  To investigate the serum antibodies in neonates with non-ABO hemolytic disease, and to provide a reference for the prevention and treatment of this disease.
Methods  Serum antibodies were detected for 30 neonates with non-ABO hemolytic disease. The mothers of 25 neonates had a child-bearing history, the mothers of 22 neonates had a history of abortion, and the mothers of 2 neonates had their first child.
Results  Of all neonates,16 had anti-D antibody and 1 had anti-D and anti-E antibodies, accounting for 56.7%; 5 had anti-E antibody,5 had anti-E and anti-c antibodies, and 1 had anti-E and anti-Jkb antibodies, accounting for 36.7%; 1(3.3%) had anti-C antibody and 1(3.3%) had anti-M antibody in MNS antigen system.
Conclusion  Antepartum screening of irregular antibodies should be performed for pregnant women, and E antigen detection should be performed for those with a child-bearing history or a history of abortion.
更新日期/Last Update: 2017-08-13