[1]刘惠,王娈,赵宇航,等.AIP与2型糖尿病周围神经病变的相关性[J].青岛大学医学院学报,2017,53(03):276-279.[doi:10.13361/j.qdyxy.201703007]
 LIU Hui,WANG Luan,ZHAO Yuhang,et al.ASSOCIATION BETWEEN ATHEROGENIC INDEX OF PLASMA AND DIABETIC PERIPHERAL NEUROPATHY[J].Acta Aacademiae Medicinae Qingdao,2017,53(03):276-279.[doi:10.13361/j.qdyxy.201703007]
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AIP与2型糖尿病周围神经病变的相关性()
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《青岛大学医学院学报》[ISSN:1672-4488/CN:37-1356/R]

卷:
第53卷
期数:
2017年03期
页码:
276-279
栏目:
出版日期:
2017-08-07

文章信息/Info

Title:
ASSOCIATION BETWEEN ATHEROGENIC INDEX OF PLASMA AND DIABETIC PERIPHERAL NEUROPATHY
文章编号:
1672-4488(2017)03-0276-04
作者:
刘惠1王娈2赵宇航1马瑞欣1
青岛大学附属医院,山东 青岛 266003 1 内分泌科; 2 内分泌实验室
Author(s):
LIU Hui WANG Luan ZHAO Yuhang MA Ruixin
Department of Endocrinology, The Affiliated Hospital of Qiingdao University, Qingdao 266003, China
关键词:
糖尿病2型糖尿病神经病变血浆致动脉粥样硬化指数危险因素
Keywords:
diabetes mellitus type 2 diabetic neuropathies atherogenic index of plasma risk factors
分类号:
R587.25
DOI:
10.13361/j.qdyxy.201703007
文献标志码:
A
摘要:
目的 研究血浆致动脉粥样硬化指数(AIP)与2型糖尿病周围神经病变的相关性。
方法 选取2型糖尿病病人426例,其中糖尿病非周围神经病变组154例,糖尿病周围神经病变组272例。根据AIP值四分位数分为A组(AIP<-0.125 8)107例、B组(AIP -0.125 9~0.046 4)107例、C组(AIP 0.046 5~0.261 6)106例、D组(AIP≥0.261 7)106例,检测并比较各组周围神经病变情况。
结果 2型糖尿病周围神经病变组的AIP值明显高于非周围神经病变组(t=2.975,P<0.05)。A、B、C、D组2型糖尿病周围神经病变所占比例分别为15.81%、25.37%、27.21%、31.62%,各组比较差异有显著性(χ2=2.754,P<0.05)。Logistic回归分析表明,AIP是2型糖尿病周围神经病变的独立危险因素(OR=2.018,95%CI=1.005~3.966,P<0.05)。
结论 AIP值升高与2型糖尿病周围神经病变相关。
Abstract:
Objective  To investigate the association between atherogenic index of plasma (AIP) and diabetic peripheral neuropathy (DPN) in patients with type 2 diabetes mellitus (T2DM).
Methods  A total of 462 T2DM patients were enrolled, and among these patients,154 had no DPN (non-DPN group) and 272 had DPN (DPN group). According to the quartile of AIP, these patients were divided into groups A with 107 patients (AIP<-0.125 8), B with 107 patients (AIP -0.125 9 to 0.046 4), C with 106 patients (AIP 0.046 5-0.261 6), and D with 106 patients (AIP ≥0.261 7). The degree of peripheral neuropathy was compared between groups.
Results  The DPN group had a significantly higher AIP than the non-DPN group (t=2.975,P<0.05). The proportion of patients with DPN was 15.81% in group A, 25.37% in group B, 27.21% in group C, and 31.62% in group D, and there was a significant difference between groups (χ2=2.754,P<0.05). The logistic regression analysis showed that AIP was an independent risk factor for DPN (OR=2.018,95% CI=1.005-3.966,P<0.05).
Conclusion  The increase in AIP is associated with the development of DPN.
更新日期/Last Update: 2017-08-13