[1]王燕,于宁,匡涌.剪切波速对不同分型儿童原发性肾病综合征诊断价值[J].青岛大学医学院学报,2017,53(03):294-296.[doi:10.13361/j.qdyxy.201703012]
 WANG Yan,YU Ning,KUANG Yong.VALUE OF SHEAR WAVE VELOCITY IN DIAGNOSIS OF DIFFERENT CLINICAL TYPES OF CHILDHOOD PRIMARY NEPHROTIC SYNDROME[J].Acta Aacademiae Medicinae Qingdao,2017,53(03):294-296.[doi:10.13361/j.qdyxy.201703012]
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剪切波速对不同分型儿童原发性肾病综合征诊断价值()
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《青岛大学医学院学报》[ISSN:1672-4488/CN:37-1356/R]

卷:
第53卷
期数:
2017年03期
页码:
294-296
栏目:
出版日期:
2017-08-07

文章信息/Info

Title:
VALUE OF SHEAR WAVE VELOCITY IN DIAGNOSIS OF DIFFERENT CLINICAL TYPES OF CHILDHOOD PRIMARY NEPHROTIC SYNDROME
文章编号:
1672-4488(2017)03-0294-03
作者:
王燕12于宁1匡涌2
1 青岛大学附属医院腹部超声科,山东 青岛 266003; 2 青岛市第九人民医院超声科
Author(s):
WANG Yan YU Ning KUANG Yong
Department of Ultrasound, The Affiliated Hospital of Qingdao University, Qingdao 266003, China
关键词:
剪切波速弹性成像技术儿童肾病综合征诊断
Keywords:
shear wave velocity elasticity imaging techniques child nephrotic syndrome diagnosis
分类号:
R445.1;R726.92
DOI:
10.13361/j.qdyxy.201703012
文献标志码:
A
摘要:
目的 探讨肾实质剪切波速(SWV)对不同临床分型儿童原发性肾病综合征(NS)的诊断价值。
方法 选择原发性NS病儿60例,其中单纯型组36例,肾炎型组24例,以健康体检者30例作为对照组。应用声触诊组织定量分析(VTQ)技术检测肾实质SWV,比较各组间肾实质SWV的差异,并就SWV对单纯型和肾炎型NS的诊断价值进行ROC曲线分析。
结果 单纯型组肾实质SWV与对照组比较差异无统计学意义(P>0.05),肾炎型组肾实质SWV与对照组和单纯型组比较,差异有统计学意义(F=7.19,P<0.05)。应用肾实质SWV诊断单纯型、肾炎型NS病儿的ROC曲线下面积分别为0.85、0.95,最佳截断点分别为2.56、3.04 m/s,灵敏度分别为75.1%、92.9%,特异度分别为80.9%、88.2%。
结论 肾炎型NS病儿的肾实质SWV明显快于单纯型NS,肾实质SWV对不同临床分型的NS有较高的诊断价值。
Abstract:
Objective  To investigate the value of renal shear wave velocity (SWV) in the diagnosis of different clinical types of childhood primary nephrotic syndrome (NS).
Methods  A total of 60 children with primary NS were enrolled, among whom 36 had simple-type NS and 24 had nephritic-type NS. At the same time, 30 healthy subjects who underwent physical examination were enrolled as control group. Virtual touch tissue quantification was used to measure renal SWV in all subjects, renal SWV was compared between groups, and a receiver operating characteristic (ROC) curve analysis was performed to investigate the diagnostic value of SWV in simple-and nephritic-type NS.
Results  There was no significant difference in renal SWV between the simple-type group and the control group (P>0.05); however, there was a significant difference in renal SWV between the nephritic-type group and the control group/simple-type group (F=7.19,P<0.05). The areas under the ROC curve for renal SWV to diagnose simple-and nephritic-type NS were 0.85 and 0.95, respectively, with the best cut-off values of 2.56 and 3.04 m/s, sensitivities of 75.1% and 92.9%, and specificities of 80.9% and 88.2%, respectively.
Conclusion  Children with nephritic-type NS have a higher renal SWV than those with simple type NS, and therefore, renal SWV has a high value in the diagnosis of different clinical types of NS.
更新日期/Last Update: 2017-08-13