[1]韩玉杰,袁鹰,李富元,等.胰岛素泵治疗儿童青少年T1DM血糖达标影响因素[J].青岛大学学报(医学版),2017,53(06):668-671,675.[doi:10.13361/j.qdyxy.201706010]
 HAN Yujie,YUAN Ying,LI Fuyuan,et al.INFLUENCING FACTORS FOR THE ACHIEVEMENT OF TARGET GLUCOSE CONTROL IN CHILDREN AND ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS ON AN INSULIN PUMP[J].JOURNAL OF QINGDAO UNIVERSITY (MEDICAL SCIENCES),2017,53(06):668-671,675.[doi:10.13361/j.qdyxy.201706010]
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胰岛素泵治疗儿童青少年T1DM血糖达标影响因素()
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《青岛大学学报(医学版)》[ISSN:2096-5532/CN:37-1217/R]

卷:
第53卷
期数:
2017年06期
页码:
668-671,675
栏目:
出版日期:
2018-03-21

文章信息/Info

Title:
INFLUENCING FACTORS FOR THE ACHIEVEMENT OF TARGET GLUCOSE CONTROL IN CHILDREN AND ADOLESCENTS WITH TYPE 1 DIABETES MELLITUS ON AN INSULIN PUMP
文章编号:
1672-4488(2017)06-0668-05
作者:
韩玉杰1袁鹰1李富元2孙晓方1段明1张娜1
1 青岛大学附属医院内分泌科,山东 青岛 266003; 2 临沂市中心医院内分泌科
Author(s):
HAN Yujie YUAN Ying LI Fuyuan SUN Xiaofang DUAN Ming ZHANG Na
Department of Endocrinology, The Affiliated Hospital of Qingdao University, Qingdao 266003, China
关键词:
糖尿病1型胰岛素输注系统血红蛋白A糖基化血糖影响因素分析
Keywords:
diabetes mellitus type 1 insulin infusion systems hemoglobin A glycosylated blood glucose root cause analysis
分类号:
R587.1
DOI:
10.13361/j.qdyxy.201706010
文献标志码:
A
摘要:
目的 通过了解长期使用胰岛素泵治疗的儿童及青少年1型糖尿病(T1DM)病人的血糖控制情况,探讨影响血糖达标的因素。
方法 收集68例来自青岛地区、年龄在6~18岁、使用胰岛素泵治疗3个月以上的T1DM病人的资料,包括一般资料、糖尿病自我管理信息、胰岛素使用量、实验室检查数据和家庭状况。以病人最近1个月内的糖化血红蛋白(HbA1c)<7.5%为血糖达标,采用Logistic回归模型分析血糖达标的相关因素。
结果 Logistic回归分析校正了年龄、泵治疗起始年龄、最近1周的平均空腹血糖、父母当中最高学历、复诊频率、低糖血症因素的干扰后,最近1周的平均餐后2 h血糖(OR=0.285,95%CI=0.093~0.880)、自我血糖监测频率(OR=1.939,95%CI=1.050~3.581)、能灵活使用泵的各种功能(OR=0.038,95%CI=0.002~0.628)、坚持糖尿病饮食(OR=0.070,95%CI=0.006~0.886)、家庭年收入(OR=0.019,95%CI=0.001~0.392)仍与血糖达标相关。
结论 对于使用胰岛素泵治疗的儿童及青少年T1DM病人,坚持糖尿病饮食、能灵活使用泵的各种功能、良好的餐后血糖管理、通过较高频次的自我血糖监测调整合适的胰岛素剂量是血糖达标的可控因素。
Abstract:
Objective  To investigate the status of glucose control in children and adolescents with type 1 diabetes mellitus (T1DM) on an insulin pump for a long time and influencing factors for the achievement of target glucose control.
Methods A total of 68 T1DM patients from Qingdao, China, aged 6-18 years, who had been using an insulin pump for more than 3 months were enrolled and their clinical data were collected, including general information, diabetes self-management information, the dose of insulin, laboratory findings, and family status. With HbA1c<7.5% within the past one month as the target of glucose control, the logistic regression model was used to analyze related influencing factors.
Results  After adjustment for the factors including age, age of the initiation of insulin pump, mean fasting blood glucose within the past one week, the highest education level of parents, frequency of reexamination, and hypoglycemia, the logistic regression analysis showed that mean 2 h postprandial plasma glucose within the past one week (odds ratio (OR)=0.285,95% confidence interval (CI)=0.093-0.880), frequency of blood glucose self-monitoring (OR=1.939,95% CI=1.050-3.581), flexibility to use various functions of the pump (OR=0.038,95%CI=0.002-0.628), adherence to diabetic diet (OR=0.070,95% CI=0.006-0.886), and annual household income (OR=0.019,95% CI=0.001-0.392) were still associated with the achievement of target glucose control.
Conclusion  As for children and adolescents with T1DM using an insulin pump, adherence to diabetic diet, flexible use of various functions of the insulin pump, good postprandial blood glucose management, and adjustment of insulin dose via high-frequency blood glucose self-monitoring are controllable factors for the achievement of target glucose control.
更新日期/Last Update: 2018-03-24