[1]吕乐乐,史同新,王君,等.幽门螺杆菌感染与口腔扁平苔藓相关性Meta分析[J].青岛大学学报(医学版),2017,53(06):707-710.[doi:10.13361/j.qdyxy.201706020]
 L Lele,SHI Tongxin,WANG Jun,et al.ASSOCIATION BETWEEN HELICOBACTER PYLORI INFECTION AND ORAL LICHEN PLANUS: A META-ANALYSIS[J].JOURNAL OF QINGDAO UNIVERSITY (MEDICAL SCIENCES),2017,53(06):707-710.[doi:10.13361/j.qdyxy.201706020]
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幽门螺杆菌感染与口腔扁平苔藓相关性Meta分析()
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《青岛大学学报(医学版)》[ISSN:2096-5532/CN:37-1217/R]

卷:
第53卷
期数:
2017年06期
页码:
707-710
栏目:
出版日期:
2018-03-21

文章信息/Info

Title:
ASSOCIATION BETWEEN HELICOBACTER PYLORI INFECTION AND ORAL LICHEN PLANUS: A META-ANALYSIS
文章编号:
1672-4488(2017)06-0707-04
作者:
吕乐乐1史同新1王君1华骋2
青岛大学附属医院,山东 青岛 266003 1 皮肤科; 2 美容整形科
Author(s):
L Lele SHI Tongxin WANG Jun HUA Cheng
Department of Dermatology, The Affiliated Hospital of Qingdao University, Qingdao 266003, China
关键词:
扁平苔癣口腔幽门螺杆菌病因学Meta分析
Keywords:
lichen planus ora Helicobacter pylori pathogenesis Meta-analysis
分类号:
R781.5;R377
DOI:
10.13361/j.qdyxy.201706020
文献标志码:
A
摘要:
目的 探讨幽门螺杆菌感染与口腔扁平苔藓发生的病因学关系。
方法 计算机检索中国期刊全文数据库(CNKI)、维普学术期刊数据库(VIP)、万方学术期刊数据库、Pubmed数据库,筛选之后纳入幽门螺杆菌感染与口腔扁平苔藓关系的相关文献,对所得数据进行Meta分析。
结果 入选的9项研究之间存在异质性(I2=87.5%,P<0.01)。Meta分析显示,口腔扁平苔藓病人幽门螺杆菌感染率(47.51%)明显高于对照组(29.54%),差异有统计学意义(Z=2.81,P<0.05)。回归分析显示,不同检测方法不是异质性来源的因素,不同来源地区是异质性来源的因素。亚组分析显示,不同来源地区对结果会产生影响。
结论 幽门螺杆菌感染与口腔扁平苔藓的发生可能存在相关性。
Abstract:
Objective  To investigate the association between Helicobacter pylori infection and oral lichen planus from the aspect of etiology.
Methods  CNKI, VIP, Wanfang Data, and PubMed were searched for articles on the association between Helicobacter pylori infection and oral lichen planus.
Results  A total of 9 studies were included, and there was heterogeneity between them (I2=87.5%,P<0.01). The Meta-analysis showed that the oral lichen planus group had a significantly higher Helicobacter pylori infection rate than the control group (47.51% vs 29.54%,Z=2.81,P<0.05). The regression analysis showed that different detection methods were not factors for heterogeneous sources, while different areas were factors for heterogeneous sources. The subgroup analysis showed that different areas had certain influence on results.
Conclusion  Helicobacter pylori infection may be associated with the development of oral lichen planus.
更新日期/Last Update: 2018-03-24