[1]张晓彤,刘丽君,滕继军,等. 高血压脑出血病人颅内血管状态及其相关危险因素[J].青岛大学学报(医学版),2018,54(03 ):367-370,372.[doi:10.11712/jms201803027]
 ZHANG Xiaotong,LIU Lijun,TENG Jijun,et al. FEATURES OF INTRACRANIAL VESSELS IN PATIENTS WITH HYPERTENSIVE INTRACEREBRAL HEMORRHAGE AND RELATED RISK FACTORS[J].JOURNAL OF QINGDAO UNIVERSITY (MEDICAL SCIENCES),2018,54(03 ):367-370,372.[doi:10.11712/jms201803027]
点击复制

 高血压脑出血病人颅内血管状态及其相关危险因素()
分享到:

《青岛大学学报(医学版)》[ISSN:2096-5532/CN:37-1217/R]

卷:
第54卷
期数:
2018年03 期
页码:
367-370,372
栏目:
出版日期:
2018-05-29

文章信息/Info

Title:
 FEATURES OF INTRACRANIAL VESSELS IN PATIENTS WITH HYPERTENSIVE INTRACEREBRAL HEMORRHAGE AND RELATED RISK FACTORS
作者:
 张晓彤1刘丽君1滕继军1孙秀萍2
 青岛大学,山东 青岛 266555 1 附属医院黄岛分院神经内科; 2 校医院
Author(s):
 ZHANG Xiaotong LIU Lijun TENG Jijun SUN Xiuping
 Department of Neurology, The Affiliated Hospital of Qingdao University, Qingdao 266555, China
关键词:
 颅内出血高血压性颅内动脉疾病卒中危险因素
Keywords:
 intracranial hemorrhage hypertensive intracranial arterial diseases stroke risk factors
分类号:
R743.34
DOI:
10.11712/jms201803027
文献标志码:
A
摘要:
 目的 探讨高血压脑出血病人颅内血管状态特点并分析其相关危险因素,为高血压脑出血病人病情评估、治疗及二级预防提供参考依据。
方法  选择2014年1月-2017年2月我科收治的急性高血压脑出血病人为研究对象,所有病人入院均采用CT检查确诊,早期完善颅脑MRI、MRA或CTA、SWI检查。收集病人的临床资料、实验室检验结果、影像学资料,并运用卡方检验、t检验、多因素Logistic回归分析进行数据处理。
结果  本研究纳入342例急性高血压脑出血病人,根据颅内血管状态分为4组。仅存在颅内动脉狭窄组76例(22.2%),仅存在脑小血管病组45例(13.2%),同时存在颅内动脉狭窄及脑小血管病组15例(4.4%),无颅内动脉狭窄和脑小血管病组206例(60.2%)。Logistic回归分析显示,与无颅内动脉狭窄组相比,存在颅内动脉狭窄病人年龄较大(OR=2.446,95%CI=1.377~4.347,P<0.05),糖尿病病史者较多(OR=1.811,95%CI=1.035~3.168,P<0.05)。与无脑小血管病组比,存在脑小血管病病人年龄较大(OR=2.354,95%CI=1.121~4.945,P<0.05)。
结论 
高血压脑出血病人可合并颅内动脉狭窄或脑小血管病变。年龄、糖尿病是存在颅内动脉狭窄的独立危险因素,年龄是存在脑小血管病的独立危险因素。
Abstract:
 Objective To investigate the features of intracranial vessels in patients with hypertensive intracerebral hemorrhage and related risk factors, and to provide a reference for disease evaluation, treatment, and secondary prevention of hypertensive intracerebral hemorrhage.
Methods The patients with acute hypertensive intracerebral hemorrhage who were admitted to our department from January 2014 to February 2017 were enrolled. All patients underwent computed tomography on admission to make a confirmed diagnosis, and magnetic resonance imaging, magnetic resonance angiography or computed tomography angiography, and susceptibility-weighted imaging were performed in the early stage after admission. The clinical data, laboratory results, and imaging data were collected, and the chi-square test, the t-test, and a multivariate logistic regression analysis were used for data management.
Results A total of 342 patients with acute hypertensive intracerebral hemorrhage were enrolled and divided into four groups according to the status of intracranial vessels. Of all patients,76 (22.2%) had intracranial arterial stenosis alone,45 (13.2%) had cerebral small vessel disease alone,15 (4.4%) had both intracranial arterial stenosis and cerebral small vessel disease, and 206 (60.2%) had no intracranial arterial stenosis or cerebral small vessel disease. The logistic regression analysis showed that compared with the group without intracranial arterial stenosis, the group with intracranial arterial stenosis had a significantly higher age (odds ratio (OR)=2.446,95% confidence interval (CI)=1.377-4.347, P<0.05) and a significantly higher proportion of patients with a history of diabetes (OR=1.811,95% CI=1.035-3.168, P<0.05). Compared with the group without cerebral small vessel disease, the group with cerebral small vessel disease had a significantly higher age (OR=2.354,95% CI=1.121-4.945, P<0.05).
Conclusion Patients with hypertensive intracerebral hemorrhage may be complicated by intracranial arterial stenosis or cerebral small vessel disease. Old age and diabetes are independent risk factors for intracranial arterial stenosis, and old age is an independent risk factor for cerebral small vessel disease.
更新日期/Last Update: 2018-06-05