[1]赵颖洁,田字彬,鞠辉,等.改良经口内镜下肌切开术与其传统术式治疗贲门失弛缓症效果比较[J].青岛大学学报(医学版),2018,54(04):454-457.[doi:10.11712/jms201804019]
 ZHAO Yingjie,TIAN Zibin,JU Hui,et al.EFFICACY OF MODIFIED PERORAL ENDOSCOPIC MYOTOMY VERSUS TRADITIONAL PERORAL ENDOSCOPIC MYOTOMY IN TREATMENT OF ACHALASIA OF CARDIA[J].JOURNAL OF QINGDAO UNIVERSITY (MEDICAL SCIENCES),2018,54(04):454-457.[doi:10.11712/jms201804019]
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改良经口内镜下肌切开术与其传统术式治疗贲门失弛缓症效果比较()
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《青岛大学学报(医学版)》[ISSN:2096-5532/CN:37-1217/R]

卷:
第54卷
期数:
2018年04期
页码:
454-457
栏目:
出版日期:
2018-07-05

文章信息/Info

Title:
EFFICACY OF MODIFIED PERORAL ENDOSCOPIC MYOTOMY VERSUS TRADITIONAL PERORAL ENDOSCOPIC MYOTOMY IN TREATMENT OF ACHALASIA OF CARDIA
文章编号:
2096-5532(2018)04-0454-04
作者:
赵颖洁田字彬鞠辉隋云龙李兴杰孙璇
(青岛大学附属医院消化内科,山东 青岛 266003)
Author(s):
ZHAO Yingjie TIAN Zibin JU Hui SUI Yunlong LI Xingjie SUN Xuan
(Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao 266003, China)
关键词:
食管失弛症经口内镜下肌切开术治疗结果
Keywords:
esophageal achalasia peroral endoscopic myotomy treatment outcome
分类号:
R571
DOI:
10.11712/jms201804019
文献标志码:
A
摘要:
目的 比较改良经口内镜下肌切开术(Liu-POEM)与传统经口内镜下肌切开术(POEM)治疗贲门失弛缓症的效果。
方法 贲门失弛缓症病人69例,应用POEM治疗42例,Liu-POEM治疗27例,比较两组手术效果、术后短期复发率、手术时间、并发症等。
结果 两组病人均顺利完成手术,且所有病人胸痛、反流、吞咽困难等贲门失弛缓症症状均较术前明显缓解。POEM组、Liu-POEM组术后3个月和6个月Eckardt评分比较差异均无统计学意义(P>0.05)。两组术后3、6个月Eckardt评分比较,差异无显著性(P>0.05);两组术后6个月LES压力比较,差异无统计学意义(P>0.05)。Liu-POEM组手术时间明显短于POEM组,差异有统计学意义(Z=6.04,P<0.05);Liu-POEM组术后气体相关并发症的发生率低于POEM组,差异有统计学意义(P=0.03)。
结论 传统POEM和Liu-POEM均能显著缓解贲门失弛缓症的临床症状,且短期疗效和复发率无差别,但Liu-POEM的手术时间及气体相关并发症较传统POEM显著减少。
Abstract:
Objective To compare the efficacy of modified peroral endoscopic myotomy (Liu-POEM) versus traditional POEM in the treatment of achalasia of cardia.
Methods A total of 69 patients with achalasia of cardia were included in this study. Of these 69 patients, 42 received POEM, and 27 received Liu-POEM. Postoperative outcome, short-term recurrence rate, operation duration and complications were compared between the two groups.
Results Surgery was successful in both groups, and symptoms of achalasia including stethalgia, reflux, and dysphagia were significantly improved in all patients after the surgery. There were no significant differences in Eckardt scores at 3 and 6 months post-surgery between the two groups (P>0.05). There was also no significant difference in lower esophageal sphincter pressure at 6 months post-surgery between the two groups (P>0.05). Operation duration was significantly shorter in the Liu-POEM group than in the POEM group (Z=6.04,P<0.05). Furthermore, the incidence rate of postoperative gas-related complications was significantly lower in the Liu-POEM group than in the POEM group (P=0.03).
Conclusion Both traditional POEM and Liu-POEM significantly reduce the clinical symptoms of achalasia, and are similar in terms of short-term efficacy and recurrence rate. However, Liu-POEM has a significantly shorter operation time and a significantly lower incidence rate of gas-related complications than traditional POEM.
更新日期/Last Update: 2018-07-08